A Longitudinal Item Response Theory Model to Characterize Cognition Over Time in Elderly Subjects
نویسندگان
چکیده
منابع مشابه
A Longitudinal Item Response Theory Model to Characterize Cognition Over Time in Elderly Subjects
For drug development in neurodegenerative diseases such as Alzheimer's disease, it is important to understand which cognitive domains carry the most information on the earliest signs of cognitive decline, and which subject characteristics are associated with a faster decline. A longitudinal Item Response Theory (IRT) model was developed for the Basel Study on the Elderly, in which the Consortiu...
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BACKGROUND The occurrence of response shift (RS) in longitudinal health-related quality of life (HRQoL) studies, reflecting patient adaptation to disease, has already been demonstrated. Several methods have been developed to detect the three different types of response shift (RS), i.e. recalibration RS, 2) reprioritization RS, and 3) reconceptualization RS. We investigated two complementary met...
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How critical is the concept of the latent trait to modern test theory ? The appeal to some unobservable characteristic modulating response probability can lead to some confusion and misunderstanding among users of psychometric technology. This paper looks at a geometric formulation of item response theory that avoids the need to appeal to unobservables. It draws on concepts in differential geom...
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BACKGROUND Better understanding of acute stress responses is important for revision of DSM-5. However, the latent structure and relationship between different aspects of acute stress responses haven't been clarified comprehensively. Bifactor item response model may help resolve this problem. OBJECTIVE The purpose of this study is to develop a statistical model of acute stress responses, based...
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ژورنال
عنوان ژورنال: CPT: Pharmacometrics & Systems Pharmacology
سال: 2017
ISSN: 2163-8306
DOI: 10.1002/psp4.12219